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Does CBD Ointment Get in Your Bloodstream?
Learn how CBD topicals like ointments and creams work when applied to the skin, their benefits, and whether they enter the bloodstream with Sunmed.
CBD topicals such as ointments, creams, and balms, have become a popular way to incorporate hemp-derived cannabinoids into daily wellness routines. Many people use them for targeted relief, applying them directly to areas of tension or discomfort — but does CBD ointment absorb into the bloodstream like tinctures, edibles, or vapes?
The short answer: no.
While CBD products like tinctures and capsules are designed for systemic absorption, ointments stay localized, interacting with the skin and underlying tissues without entering the bloodstream. This makes them a great choice for people looking for targeted benefits without the full-body effects associated with ingestible CBD.
Want to learn more about how CBD topicals work and their benefits? We’re here to break it down.
What is CBD?
CBD (cannabidiol) is a naturally occurring compound found in the hemp plant. It belongs to a group of plant-based compounds called cannabinoids, which interact with the body's endocannabinoid system (ECS). This complex cell-signaling network plays a key role in maintaining balance in the body.*
Unlike THC, CBD is not psychoactive, meaning it does not cause a high.* Instead, it works by interacting with cannabinoid receptors (CB1 and CB2), which are found throughout the central and peripheral nervous system, immune system, and skin. This interaction influences various physiological processes, including stress response, discomfort regulation, and skin health.*
CBD’s effects depend on how it is consumed. While ingestible forms like tinctures, gummies, and capsules work systemically, topicals are applied directly to the skin, offering a more targeted approach, making them a popular choice for direct application to the skin.
How do CBD topicals work?
CBD topicals — such as. This offerss, balms, and ointments — are hemp-derived formulations designed for direct applhe skin. Unlike oral CBD products, which enter the digestive system and circulate throughout the body, topicals work locally to provide targeted effects.
Most CBD ointments include:
- CBD extract: Either full spectrum, broad spectrum, or isolate.
- Carrier oils: Carrier oils like coconut oil, shea butter, or jojoba oil help spread the product evenly.
- Essential oils and botanical extracts: Other botanical extracts and natural ingredients can provide additional benefits. For instance, lavender can provide relaxation, menthol can offer a cooling sensation, and shea butter can add nourishing hydration.
When applied to the skin, these products can interact with cannabinoid receptors in the epidermis and dermis, as well as other skin components like TRPV1 receptors, which are involved in temperature and discomfort perception.*
Does CBD ointment enter the bloodstream?
When applied topically, CBD can work with the receptors directly beneath the skin at the point of application to influence local processes, such as addressing minor skin issues or easing localized discomfort.*
However, CBD topicals do not typically enter the bloodstream due to the skin's protective barrier function.
How does the skin function?
The skin is the body’s first line of defense, protecting against environmental factors, toxins, and unwanted substances. While it can absorb certain compounds, its multiple layers act as a strong barrier, limiting what reaches the bloodstream.
The outermost layer, the epidermis, is made up of tightly packed cells that prevent large molecules, including cannabinoids like CBD, from passing through easily. Beneath the epidermis is the dermis, which contains nerve endings, blood vessels, and connective tissue.
Even though CBD interacts with receptors in this layer, it does not typically penetrate deep enough to enter systemic circulation.
For CBD to reach the bloodstream, it would need to pass through the hypodermis (subcutaneous fat layer) and into the capillaries, which traditional CBD ointments are not formulated to do. This is why CBD ointments provide localized effects without producing full-body absorption.
Some products, like transdermal patches, contain ingredients that help CBD bypass these skin barriers. These are specifically designed to deliver cannabinoids into the bloodstream. However, standard CBD creams and ointments remain surface-level, making them ideal for targeted applications without systemic effects.
Will CBD ointments show up on a drug test?
Traditional CBD ointments do not enter the bloodstream, which means they are highly unlikely to show up on a drug test.* Since drug tests screen for THC or its metabolites in blood, urine, or saliva, topically applied CBD does not contribute to detectable THC levels.
However, there are some exceptions. Transdermal patches may introduce CBD (and THC, if present) into the bloodstream, increasing the risk of detection.
Full spectrum CBD ointments contain trace amounts of THC, but since the cannabinoids stay in the skin, they do not enter systemic circulation at detectable levels. It is important to note, however, that extended or excessive use of high-potency topicals over a large area has not been widely studied, but standard applications do not lead to positive drug test results.
Misinformation about CBD absorption has led to concerns about topical use and drug testing. If avoiding THC is a priority, broad spectrum or CBD isolate-based ointments offer an extra level of assurance. As always, third-party lab reports can confirm a product’s cannabinoid content.
What are the potential benefits of CBD topicals?
CBD ointments provide a targeted, non-systemic approach, offering unique advantages over ingestible CBD products.
Localized effects for targeted relief
Because CBD ointments interact with receptors in the skin and underlying tissues, they are ideal for specific areas of discomfort or tension. Instead of circulating throughout the body, the cannabinoids stay where they are applied, directly influencing local ECS receptors.
No systemic effects
Unlike tinctures or gummies, CBD ointments do not cause full-body effects like drowsiness, relaxation, or mood changes. This makes them a great option for those who want focused support without systemic impact. They are also less likely to interfere with other drugs or medication, as ingested forms of CBD may.*
Works alongside oral CBD
CBD ointments can be combined with tinctures, gummies, or capsules for a multi-layered approach. Topicals address external concerns, while ingestibles support internal balance. This flexibility allows users to tailor CBD use to their individual needs.
What to know about bioavailability for different forms of CBD
Choosing the right form of CBD depends on the desired outcome. When it comes to absorption, here are some factors to consider:
- Ointments and creams: Work locally, providing targeted effects without entering the bloodstream.
- Tinctures and edibles: Absorbed into the bloodstream, offering full-body effects, including potential mood and sleep support.*
- Vapes: Provide fast-acting, full-body effects, but wear off more quickly and can irritate or damage the lungs.
- Transdermal patches: Deliver cannabinoids gradually into the bloodstream, creating a steady systemic effect.
CBD topicals are an excellent choice for those looking for localized effects without systemic absorption.
The bottom line
CBD ointments provih the skin’s endocannabinoid system (ECS) without entering the bloodstream. Unlike ingestible CBD, topicals work locally to help soothe discomfort and tension, without entering the blood stream. They are also unlikely to appear on drug tests, making them a practical choice for daily use.
At Sunmed, we are committed to providing high-quality hemp products designed to support both your mind and body.
Our carefully formulated CBD topicals offer a science-backed, non-systemic approach to wellness, delivering soothing effects where you need them most. Explore our full range of third-party tested hemp CBD products to find the best fit for your wellness routine.
*This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources:
An introduction to the endogenous cannabinoid system | PMC
Cannabinoid receptors: where they are and what they do | PubMed