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CBD dosage for anxiety: How many mg is recommended?
Learn the basics of how CBD may help ease feelings of anxiety and learn best practices for safe, effective use with this guide.
Anxiety disorders are among the most common mental health conditions globally, affecting millions of individuals each year.
Traditional treatments — such as therapy and medication — can be effective but may come with side effects or limited accessibility. As a result, many people are exploring alternative remedies, and cannabidiol (CBD) has emerged as a popular option.
This article examines useful CBD dosages for anxiety, what to know about high-dose CBD products, and why CBD is gaining attention for its therapeutic effects.
What is anxiety?
Anxiety is a natural response to stress, characterized by feelings of tension, worried thoughts, and physical changes like increased heart rate.
While occasional anxiety is normal, persistent and excessive anxiety can interfere with daily activities and quality of life. Anxiety disorders — such as generalized anxiety disorder (GAD), panic disorder, and social anxiety disorder — are diagnosed when anxiety becomes chronic and overwhelming.
Common symptoms include:
- Excessive worrying
- Restlessness or feeling on edge
- Fatigue
- Difficulty concentrating
- Irritability
- Muscle tension
- Sleep disturbances
What is CBD?
Cannabidiol (CBD) is a non-psychoactive compound found in the cannabis plant, recognized for its potential therapeutic benefits.
Unlike tetrahydrocannabinol (THC), CBD does not produce a “high” or intoxicating effect. Instead, it is noted for its anti-inflammatory, analgesic, anxiolytic (anxiety-reducing), and neuroprotective properties.
How does CBD work in the body?
CBD interacts with the body’s endocannabinoid system (ECS) — a complex network of receptors, enzymes, and endocannabinoids that regulate various physiological processes, including mood, pain sensation, and immune function.
Specifically, CBD influences cannabinoid receptors (CB1 and CB2) and also interacts with other receptor systems such as serotonin receptors, which play a key role in mood regulation.
How might CBD help with anxiety?
There are a few ways that CBD may be able to help with feelings of anxiety and overwhelm. Here’s what you should know.
Anxiolytic effects
Research suggests that CBD may reduce anxiety by interacting with serotonin receptors in the brain. Serotonin is a neurotransmitter crucial for mood regulation, and imbalances in serotonin signaling are closely linked to anxiety disorders.
Reducing inflammation
Chronic inflammation is associated with the development of anxiety and other mental health disorders. CBD’s anti-inflammatory properties may help with this inflammation, potentially alleviating anxiety symptoms.
Neuroprotective benefits
CBD also offers neuroprotective benefits, safeguarding brain cells from damage and supporting overall brain health. These effects can be beneficial for individuals experiencing anxiety related to neurodegenerative conditions or brain injuries.
How to determine the right amount of CBD
Several factors influence the appropriate CBD dosage for anxiety, including:
- Body Weight: Heavier individuals may require higher doses for the same effect.
- Severity of Anxiety: More severe symptoms may call for higher dosages.
- Individual Metabolism: Metabolic rates affect how quickly the body processes CBD.
- Method of Consumption: Inhalation methods (smoking/vaping) often require lower dosages than oral ingestion.
- Tolerance Levels: Regular CBD users may develop a tolerance and need higher doses over time.
General dosage guidelines
While there is no one-size-fits-all dosage for CBD, here are broad recommendations:
- Low Dose: 5-100 mg daily (mild anxiety or a starting point).
- Medium Dose: 100-500 mg per day (moderate anxiety symptoms).
- High Dose: 900 mg per day or more (severe anxiety or when lower doses prove ineffective).
It’s best to start with a low dose and gradually increase until you achieve the desired effect. Consulting with a healthcare professional can help tailor dosage recommendations based on individual needs and health conditions.
What does the research say about CBD dosage for anxiety?
When thinking about CBD doses, specifically for anxiety, it’s helpful to take a look at some of the existing research.
CBD and generalized anxiety disorder
A study published in The Permanente Journal investigated the effects of CBD on individuals with generalized anxiety disorder. Participants received a daily dose of 25 mg of CBD for four weeks and showed a significant reduction in anxiety levels, with 79.2% experiencing lower anxiety scores during the first month.
CBD for Social Anxiety Disorder
Research published in Neuropsychopharmacology explored CBD’s impact on individuals with social anxiety disorder (SAD). Participants received a single dose of 600 mg of CBD before a public-speaking test.
Compared to a placebo, CBD significantly reduced anxiety, cognitive impairment, and discomfort during the test.
CBD and PTSD-Related Anxiety
The same study in the Permanente Journal examined the use of CBD in participants with PTSD, providing doses ranging from 25 mg to 175 mg daily. The findings suggested that higher doses were more effective in reducing PTSD-related anxiety and improving sleep quality.
Dose-Response Relationship of CBD
A review article by The Neurotherapeutics Journal assessed multiple studies on CBD dosage and anxiolytic effects. Dosages between 10 mg and 600 mg showed efficacy in reducing anxiety, with higher doses often delivering more significant relief. However, the optimal dosage varied based on the specific anxiety disorder and individual factors.
Are there risks of using CBD?
As with any wellness product, it’s important to be mindful of potential side effects. While CBD is widely regarded as safe, be mindful of the following:
Side effects
Although CBD is generally well-tolerated, high doses can increase the risk of:
- Drowsiness
- Digestive issues
- Dry mouth (“cottonmouth”)
- Dizziness
CBD may also interact with medications metabolized by the liver, potentially altering drug effectiveness or concentration. Those taking medications should consult a healthcare provider before starting high-dose CBD.
Legal considerations
CBD legality varies by region. In many areas, hemp-derived CBD with less than 0.3% THC is legal, but regulations differ. Always purchase CBD from reputable manufacturers that comply with local laws.
Quality and purity
The safety and effectiveness of CBD hinge on product quality. Users, especially those taking higher doses, should opt for third-party lab-tested products to ensure they are free of contaminants like pesticides, heavy metals, and residual solvents.
What are some best practices for using CBD for anxiety?
If you’re getting started with CBD, there are a few best practices that are helpful to keep in mind:
- Start Low and Go Slow: Begin with a low dose and gradually increase until you find the level that works for you.
- Consult a Healthcare Professional: Especially crucial if you have underlying health conditions or take other medications. A medical professional can tailor dosage recommendations to your unique needs.
- Choose High-Quality Products: Look for third-party lab testing to confirm potency and purity.
- Monitor Your Response: Keep track of your anxiety levels, mood changes, and any side effects. Adjust the dosage as needed.
- Maintain Consistency: Regular, consistent use helps sustain steady CBD levels in your system, maximizing potential benefits.
The bottom line
CBD has garnered attention as a promising option for managing anxiety, providing potential benefits without the intoxicating effects of THC.
Research shows that dosages ranging from 10 mg to 600 mg can be effective, and anecdotal evidence points to growing interest in higher-dose regimens for severe pain, inflammation, and anxiety. While high-dose CBD may offer enhanced relief, it also carries an increased risk of side effects and potential drug interactions.
Those interested in high-dose CBD should proceed with caution — prioritizing medical guidance, high-quality products, and vigilant self-monitoring. As research on CBD continues, clearer guidelines will likely emerge, helping individuals make informed decisions about the best CBD dosage for their unique needs.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources:
Cannabis Use for Anxiety and Sleep: A Large Case Series | The Permanente Journal
Effects of Cannabidiol (CBD) on Regional Cerebral Blood Flow | NCBI
Cannabidiol as a Potential Treatment for Anxiety Disorders | Neurotherapeutics Journal