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CBD oil vs. gabapentin for nerve pain
Learn how CBD and gabapentin help ease nerve discomfort, their differences and risks, and which may be right for you with Sunmed.
Nerve discomfort is a prevalent issue that can range from mild tingling to intense sensations that significantly impact quality of life.
When exploring ways to manage nerve discomfort, two options often come up: gabapentin, a commonly prescribed medication, and CBD oil, a hemp-derived wellness supplement.
Understanding how these options work and their differences can help you make a more informed decision. We’re here to break down their differences and help you find a path to relief.
What is gabapentin?
Gabapentin is a prescription medication classified as an anticonvulsant, and it’s widely used to manage nerve-related discomfort. It’s particularly common for conditions such as neuropathy, where nerves send abnormal signals to the brain, creating sensations that range from tingling to sharp pain.
Initially developed to manage seizures, gabapentin was later found to be effective for nerve discomfort. It’s now often prescribed for conditions like diabetic neuropathy, postherpetic neuralgia, and other nerve-related issues.
How does gabapentin work?
Gabapentin affects the way nerves communicate with the brain. Our nervous system relies on electrical signals to transmit information, and overactive nerves can sometimes send too many signals, overwhelming the brain. Gabapentin helps regulate this activity by interacting with specific proteins in the brain called calcium channels.
Gabapentin mirrors the effects of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter known to temporarily limit a nerve cell’s ability to receive and send messages to other neurons in the brain. In the case of nerve discomfort, neurons transmit pain signals, so GABA can help ease related discomfort.
Gabapentin helps calm the nervous system by mirroring GABA and helping calm excessive neurotransmitter release, alleviating the intensity of nerve-related discomfort.
What is CBD oil?
CBD oil is a natural supplement derived from hemp, a variety of the Cannabis sativa plant. Unlike THC, the psychoactive compound in cannabis, CBD does not produce intoxicating effects. Instead, it interacts with the body’s internal systems to support overall wellness.
CBD is short for cannabidiol, one of many cannabinoids found in hemp. These compounds interact with the body’s endocannabinoid system (ECS), a network of receptors and enzymes that help maintain balance across various functions, including mood, immune response, and the nervous system.*
How does CBD work?
The ECS plays a critical role in regulating homeostasis, which is the body’s ability to maintain internal balance despite external changes. The ECS has two primary types of receptors: CB1 receptors, found mainly in the brain and central nervous system, and CB2 receptors, found throughout the immune system and peripheral tissues.*
CBD doesn’t directly bind to these receptors like THC does. Instead, it influences the ECS more indirectly, supporting the role of the body’s own internally produced cannabinoids, called endocannabinoids. These endocannabinoids help modulate the nervous system, potentially promoting relaxation and easing nerve discomfort.*
CBD also interacts with other pathways in the body, including serotonin receptors, which play a role in both emotional wellness and neuropathic discomfort.* By supporting multiple systems, CBD oil offers a holistic approach to managing nerve discomfort.
How does CBD oil compare to gabapentin for nerve discomfort?
When deciding between gabapentin and CBD oil, it’s helpful to consider their effectiveness, mechanisms, and how they fit into your lifestyle. Both options offer unique benefits, but their approach to managing nerve discomfort differs significantly.
Effectiveness and mechanism
Gabapentin is designed to target nerve signaling directly. By modulating calcium channels, it reduces the intensity of abnormal nerve signals that cause discomfort. It is especially effective for more severe nerve issues that require medical supervision.
CBD oil takes a broader approach. Instead of targeting nerve signals directly, it supports the body’s natural regulatory systems through the ECS.
By promoting balance within the nervous system and interacting with other pathways like serotonin receptors, CBD may help reduce the overall intensity of nerve-related sensations while supporting emotional and physical wellness.*
Side effects
Gabapentin is a prescription medication that may cause side effects such as drowsiness, dizziness, or fatigue. Because it alters how the brain processes nerve signals, some people experience more serious side effects such as mood changes, memory loss, or challenges with concentration or coordination.
CBD oil, when used as directed, is extremely well tolerated and is only associated with minor temporary side effects like nausea or drowsiness, particularly at higher serving sizes. Choosing high-quality, lab-tested CBD products ensures safety and minimizes the risk of unwanted effects.*
Accessibility and use
Gabapentin requires a prescription and regular monitoring by a healthcare provider, while CBD oil is widely available without a prescription, making it a more accessible option for everyday wellness. It can be incorporated into your routine in various ways, such as sublingual tinctures or gummies. This flexibility makes CBD an attractive choice for those seeking a natural option to support their overall health.*
Gabapentin and CBD oil can also be used in tandem. Some people use them together to support nerve health, but it’s essential to consult a healthcare provider before combining them. Your provider can help you determine the best approach based on your unique needs and medical history.
What to consider when choosing between CBD and gabapentin
Deciding between gabapentin and CBD oil — or choosing to use both — depends on your specific situation.
- Severity of Discomfort: For severe nerve-related issues, gabapentin may be a more effective option under a doctor’s guidance.
- Preference for Natural Options: If you prefer plant-based supplements, CBD oil offers a more natural alternative to traditional medications.*
- Lifestyle Factors: Gabapentin requires ongoing medical supervision, while CBD oil offers flexibility and can easily be incorporated into a wellness routine.
The bottom line
Nerve discomfort can feel overwhelming, but understanding your options is an important step toward relief. Whether you choose gabapentin, CBD oil, or a combination of both, it’s essential to base your decision on your personal goals and needs. By staying informed and seeking professional advice, you can take meaningful steps toward improved wellness and comfort.
*This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources:
Gabapentin: Uses, Side Effects, Dosages, Interactions & More | Cleveland Clinic
Physiology, GABA - StatPearls | NCBI Bookshelf
An introduction to the endogenous cannabinoid system | PMC
Cannabis‐based medicines for chronic neuropathic pain in adults | PMC
Role of 5-HT receptors in neuropathic pain: potential therapeutic implications | ScienceDirect